In our recent study, Interstate Variations on Use of Opioids, 4th Edition, WCRI looked at the concomitant use of opioids and other central nervous system depressants such as benzodiazepines (Valium® and Xanax®), muscle relaxants (Soma® and Flexeril®), and sedatives (Ambien®) among injured workers.

Several clinical guidelines, including the recently released CDC guideline for prescribing opioids for chronic pain, caution about the potential dangers of taking these medications together. 

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